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Clocortolone Pivalate

Published: July 26, 2026Updated: August 27, 2026

Clocortolone Pivalate is a topical corticosteroid medication available in cream formulation. It is used to treat inflammatory and itchy skin conditions that respond to corticosteroid therapy. The pivalate ester formulation affects the drug's lipophilicity and penetration characteristics, influencing its potency and duration of action.

Quick summary

Clocortolone Pivalate is a topical corticosteroid cream used to reduce inflammation and itching in various skin conditions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
21250
Generic
Clocortolone Pivalate
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, including eczema, dermatitis, psoriasis, and other conditions characterized by skin inflammation, redness, and itching.

As a topical corticosteroid, it works by suppressing inflammatory responses in the skin through multiple mechanisms including reducing inflammatory cell migration, decreasing vascular permeability, and modulating immune cell activity. The pivalate ester enhances the drug's lipophilicity, facilitating better penetration into skin tissue.

For external use only on the skin. Should not be applied to large body areas, broken skin, or used for prolonged periods without medical supervision. Avoid contact with eyes, mouth, and mucous membranes. Not recommended for use in children unless specifically directed by a physician. Discontinue use and consult a healthcare provider if irritation, hypersensitivity, or worsening of the condition occurs.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy