Clomiphene Citrate
Clomiphene Citrate is a selective estrogen receptor modulator (SERM) commonly prescribed to induce ovulation in women experiencing infertility due to anovulation or irregular ovulation. It is often used as a first-line treatment for infertility and is also sometimes prescribed off-label for male hypogonadism.
Clomiphene Citrate is a fertility medication that stimulates ovulation by blocking estrogen receptors in the hypothalamus.
Key facts at a glance
- RxNorm
- 142431
- Generic
- Clomiphene Citrate
- Class
- pin-variant
- Brands
- Clomid, Milophene
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used to treat anovulatory infertility in women, including conditions like polycystic ovary syndrome (PCOS). May also be used in men for hypogonadism and to improve testosterone levels.
Works by blocking estrogen receptors in the hypothalamus, tricking the body into sensing low estrogen levels. This increases release of gonadotropin-releasing hormone (GnRH), which stimulates the pituitary to release more FSH and LH, promoting ovulation.
Typically taken for 5 days at the beginning of the menstrual cycle. Common side effects include hot flashes, mood swings, and ovarian cysts. Not recommended for women with liver disease, uncontrolled thyroid disorders, or pregnancy. Multiple pregnancies (especially twins) are a known risk.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy