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Clomipramine Hydrochloride

Published: July 26, 2026Updated: August 25, 2026

Clomipramine Hydrochloride is a tricyclic antidepressant primarily used to treat obsessive-compulsive disorder (OCD). It works by increasing levels of serotonin and norepinephrine in the brain, helping to reduce compulsive behaviors and intrusive thoughts.

Quick summary

Clomipramine is a tricyclic antidepressant used mainly for OCD that works by increasing serotonin and norepinephrine levels.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
81984
Generic
Clomipramine Hydrochloride
Class
pin-variant
Brands
Caniquell, Calmera, Anafranil, Clomicalm
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Primarily prescribed for obsessive-compulsive disorder (OCD). May also be used for depression, panic disorder, and certain phobias when other treatments have not been effective.

Functions as a serotonin and norepinephrine reuptake inhibitor (SNRI), increasing these neurotransmitters in the brain to improve mood and reduce compulsive symptoms.

May cause drowsiness, dry mouth, and weight gain. Avoid alcohol and inform your doctor of any heart conditions before starting treatment. Do not stop taking abruptly without medical supervision.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy