Clonazepam
Clonazepam is a prescription benzodiazepine medication primarily used to treat seizure disorders and panic disorder. It works by enhancing the activity of GABA, a neurotransmitter that reduces brain activity, producing calming effects on the nervous system. This medication requires careful medical supervision due to risks of dependence and withdrawal.
Clonazepam is a benzodiazepine used for seizures and panic disorder that works by enhancing calming brain signals.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- N03AE01
- RxNorm
- 2598
- Generic
- Clonazepam
- Class
- atc-n03
- Brands
- Klonopin
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet, solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Clonazepam is FDA-approved for seizure disorders (including absence seizures and Lennox-Gastaut syndrome) and panic disorder. It may also be prescribed off-label for anxiety, restless leg syndrome, and certain movement disorders.
Clonazepam enhances the effects of gamma-aminobutyric acid (GABA), the brain's primary inhibitory neurotransmitter. This increases chloride channel opening, reduces neuronal excitability, and produces sedative, anticonvulsant, and anxiolytic effects.
This medication carries a high risk of physical dependence and tolerance with prolonged use. It should not be stopped abruptly, as withdrawal can be severe. Patients should avoid alcohol and operate machinery until they understand how clonazepam affects them. Use during pregnancy is generally not recommended due to potential fetal risks.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy