Cloprostenol Sodium
Cloprostenol Sodium is a synthetic prostaglandin F2α analog primarily used in veterinary medicine to manage reproductive functions in livestock, particularly cattle. It works by inducing luteolysis, causing regression of the corpus luteum, which allows for estrus synchronization, treatment of reproductive disorders, and induction of parturition or pregnancy termination when medically necessary.
Cloprostenol Sodium is a prostaglandin analog used in veterinary medicine primarily for reproductive management in cattle through induction of luteolysis.
Key facts at a glance
- RxNorm
- 204179
- Generic
- Cloprostenol Sodium
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Synchronization of estrus in cattle for breeding programs, treatment of pyometra and endometritis, induction of parturition in cattle, termination of unwanted pregnancies, and luteolysis induction for reproductive management in various livestock species.
As a prostaglandin F2α analog, Cloprostenol Sodium causes regression of the corpus luteum (luteolysis) in the ovary, which leads to a decrease in progesterone levels, allowing estrus to occur and enabling treatment of progesterone-dependent conditions.
This medication is intended exclusively for veterinary use. Proper administration timing relative to the estrous cycle is critical for efficacy. Should only be administered by qualified veterinary professionals. May cause side effects including restlessness, sweating, and abdominal discomfort in treated animals. Contraindicated in pregnant animals unless termination is the intended outcome.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy