Coagulation Factor Ix, Human
Coagulation Factor IX, Human is a recombinant or plasma-derived clotting factor replacement therapy used to treat and prevent bleeding episodes in patients with hemophilia B, a genetic bleeding disorder caused by deficiency of clotting factor IX. It is administered intravenously and can be used for on-demand treatment of acute bleeding, routine prophylaxis to prevent bleeding, and management of surgical bleeding. This medication is typically prescribed for individuals with moderate to severe hemophilia B who require factor replacement therapy.
Coagulation Factor IX is a clotting factor replacement therapy used to treat and prevent bleeding in patients with hemophilia B who lack sufficient factor IX.
Key facts at a glance
- RxNorm
- 221099
- Generic
- Coagulation Factor Ix, Human
- Class
- pin-variant
- Brands
- Kcentra, Alphanine SD
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment and prevention of bleeding episodes in hemophilia B (Christmas disease); perioperative management of surgical bleeding in factor IX-deficient patients; routine prophylaxis to prevent bleeding and reduce joint damage in eligible patients.
Replaces deficient or missing clotting factor IX in the blood, restoring the coagulation cascade and enabling normal clot formation to stop and prevent bleeding episodes.
Administered via intravenous injection; monitor for allergic reactions and inhibitors (neutralizing antibodies); dosing is individualized based on patient weight, bleeding severity, and factor IX levels; regular monitoring of factor IX activity may be required.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy