Cocaine
Cocaine is a naturally-derived local anesthetic and vasoconstrictor agent. It is used in limited medical settings for surface anesthesia of the nose, throat, and mouth during surgical and diagnostic procedures, as well as for controlling bleeding in these areas.
A local anesthetic with vasoconstrictor properties used in specific medical procedures.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- N01BC01
- RxNorm
- 2653
- Generic
- Cocaine
- Class
- atc-n01
- Brands
- Goprelto, Numbrino
- Availability
- rx
- Lactation
- unknown
- Routes
- nasal, ophthalmic, topical
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Topical anesthesia for ENT procedures, nasal and sinus surgeries, and certain ophthalmologic applications where vasoconstriction is also desired.
Blocks sodium channels in nerve fibers, preventing the generation and conduction of nerve impulses, thereby numbing the applied area. Its vasoconstrictive properties also reduce blood flow to the site.
Use is restricted to clinical settings by qualified professionals only. Carries significant risk of systemic absorption, cardiovascular effects, and CNS stimulation. Subject to strict regulatory controls due to high abuse potential.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy