Cocaine Hydrochloride
Cocaine Hydrochloride is a potent local anesthetic and vasoconstrictor historically used in limited surgical settings, particularly otolaryngologic (ENT) and ophthalmologic procedures. Due to its high abuse potential and availability of safer alternatives, its clinical use is now extremely rare and restricted to specialized medical environments.
Cocaine Hydrochloride is a controlled local anesthetic with significant abuse potential, now used only in rare, controlled medical settings.
Key facts at a glance
- RxNorm
- 81985
- Generic
- Cocaine Hydrochloride
- Class
- pin-variant
- Brands
- Goprelto, Numbrino
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Limited to topical anesthesia in upper respiratory tract surgeries, nasal procedures, and certain ophthalmologic applications where its vasoconstrictive properties provide both anesthesia and reduced bleeding.
Blocks sodium channels in nerve fibers, preventing the initiation and propagation of action potentials, thereby inhibiting sensory nerve transmission and causing local numbness.
Schedule II controlled substance with high addiction potential. Contraindicated in patients with cardiovascular disease, hypertension, or hyperthyroidism. Must be administered only by qualified personnel in controlled settings with continuous vital sign monitoring. Multiple drug interactions and risk of cardiac arrhythmias.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy