Codeine Hydrochloride
Codeine Hydrochloride is an opioid analgesic used to treat mild to moderate pain and as a cough suppressant. It works by binding to opioid receptors in the central nervous system to decrease pain perception and suppress the cough reflex. This medication is typically prescribed when other treatments have proven insufficient.
An opioid medication used for pain relief and cough suppression.
Key facts at a glance
- RxNorm
- 1115966
- Generic
- Codeine Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Relief of mild to moderate pain and suppression of dry, unproductive coughs. May be used in combination with other analgesics like acetaminophen or aspirin for enhanced pain relief.
Codeine binds to mu-opioid receptors in the brain and spinal cord, altering the perception of pain and reducing the brain's cough reflex response. It also has mild sedative effects.
Carries risk of dependence, tolerance, and addiction with prolonged use. Common side effects include drowsiness, constipation, and nausea. May cause respiratory depression in sensitive individuals. Should be used with caution and avoided in certain populations including children under 12, those with respiratory conditions, and individuals with a history of substance abuse. Always follow prescribed dosage carefully.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy