Codeine Sulfate
Codeine Sulfate is an opioid analgesic used to treat mild to moderate pain and, in some formulations, to relieve coughs. It works by binding to opioid receptors in the brain and central nervous system, altering the perception of pain and reducing the urge to cough. This medication is typically prescribed when other pain relievers like acetaminophen or NSAIDs have proven insufficient.
An opioid medication for pain relief and cough suppression that works by affecting how the brain and nervous system respond to pain.
Key facts at a glance
- RxNorm
- 91104
- Generic
- Codeine Sulfate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of mild to moderate pain and as a cough suppressant (antitussive). May be used when other analgesics are inadequate for pain management.
Binds to mu-opioid receptors in the brain and central nervous system, altering pain perception and suppressing the cough reflex through effects on the medulla's cough center.
Carries risks of dependence, tolerance, and respiratory depression. Not recommended for children under 12 or those recovering from tonsillectomy. May cause drowsiness; avoid alcohol and CNS depressants. Use with caution in patients with respiratory conditions, head injuries, or liver impairment.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy