Colfosceril Palmitate
Colfosceril Palmitate is a synthetic pulmonary surfactant used to treat respiratory distress syndrome (RDS) in premature infants. It works by reducing surface tension in the alveoli, preventing lung collapse and improving gas exchange. This medication is administered directly into the airways via endotracheal tube.
A synthetic lung surfactant used to treat breathing difficulties in premature infants by preventing alveolar collapse.
Key facts at a glance
- RxNorm
- 69782
- Generic
- Colfosceril Palmitate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used for prevention and treatment of Respiratory Distress Syndrome (RDS) in premature infants. May also be used in other conditions requiring pulmonary surfactant replacement.
Colfosceril Palmitate reduces surface tension at the air-liquid interface of the alveoli, preventing alveolar collapse during expiration and improving lung compliance and oxygenation.
Administered by trained healthcare professionals via endotracheal tube during mechanical ventilation. Transient adverse effects may include oxygen desaturation, bradycardia, and pulmonary hemorrhage. Should only be used in monitored acute care settings.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy