Hydrocodone and Acetaminophen
Combogesic is a brand-name combination medication containing paracetamol and ibuprofen, designed to provide relief from pain and fever. It is typically used for short-term management of various painful conditions where combination therapy may offer enhanced relief compared to single-agent use.
Combogesic is a paracetamol-ibuprofen combination medication used for pain and fever relief.
Key facts at a glance
- RxNorm
- 2673876
- Generic
- Combogesic
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Combogesic is used for the short-term treatment of mild to moderate pain and fever, including conditions such as headache, dental pain, muscle aches, and menstrual cramps. It may be prescribed when single-agent therapy is insufficient for adequate symptom control.
Combogesic combines paracetamol, which acts on the central nervous system to reduce pain perception and fever, with ibuprofen, an NSAID that inhibits cyclooxygenase enzymes to decrease inflammation and pain at the site of injury. The combination provides complementary mechanisms for more comprehensive symptom relief.
This medication should only be used as directed by a healthcare provider and for the shortest duration necessary. It is contraindicated in patients with known hypersensitivity to either component, severe kidney or liver impairment, active gastrointestinal bleeding, or heart failure. Caution is advised in patients with asthma, hypertension, or those taking anticoagulants. Alcohol should be avoided during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy