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Common Paper Wasp Venom Protein

Published: July 26, 2026Updated: August 31, 2026

Common Paper Wasp Venom Protein is a specialized immunotherapy treatment derived from the venom of paper wasps. It is used to desensitize individuals with confirmed IgE-mediated allergy to paper wasp venom, reducing their risk of severe systemic reactions upon future stings. This treatment is typically administered under close medical supervision in an allergist's office or clinical setting.

Quick summary

A venom immunotherapy agent used to build tolerance in patients with life-threatening paper wasp venom allergies.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 31, 2026Editorial policy

Key facts at a glance

RxNorm
1294628
Generic
Common Paper Wasp Venom Protein
Class
unclassified
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
solution
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment and prevention of systemic allergic reactions (anaphylaxis) in patients with clinically confirmed IgE-mediated allergy to paper wasp venom. Indicated for patients with history of moderate to severe reactions following wasp stings.

The mechanism involves repeated exposure to gradually increasing doses of venom allergens, which promotes immune tolerance by inducing blocking IgG antibodies, suppressing mast cell and basophil activation, and shifting the immune response from IgE-mediated hypersensitivity to a more controlled state.

Must only be administered by trained medical professionals equipped to manage anaphylaxis. Requires a build-up phase followed by maintenance doses. Not to be confused with venom skin testing materials. Contraindicated in patients with certain cardiovascular conditions. Patients should continue to avoid wasp exposure even during treatment.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 31, 2026. · Read our editorial policy