Prochlorperazine
Compazine (prochlorperazine) is a first-generation antipsychotic medication primarily used to control severe nausea, vomiting, and anxiety. It is also prescribed for the treatment of schizophrenia and other psychotic disorders when other medications have not been effective or are not suitable.
Compazine is an antipsychotic medication used to treat nausea, vomiting, anxiety, and psychotic disorders like schizophrenia.
Key facts at a glance
- RxNorm
- 203546
- Generic
- Compazine
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Compazine is used to treat severe nausea and vomiting, schizophrenia and other psychotic disorders, and generalized anxiety disorder when other treatments have not been effective.
Compazine belongs to the phenothiazine class of antipsychotics and works by blocking dopamine receptors in the brain, which helps reduce nausea and vomiting signals, as well as psychotic symptoms.
Compazine may cause drowsiness, dizziness, and extrapyramidal side effects such as involuntary movements or muscle stiffness. It should be used with caution in elderly patients with dementia-related psychosis. Inform your doctor about any history of seizures, liver disease, or heart conditions before taking this medication.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy