Concizumab-Mtci
Concizumab-Mtci is an investigational monoclonal antibody that inhibits tissue factor pathway inhibitor (TFPI), designed to restore hemostasis in individuals with hemophilia. It belongs to a novel class of non-factor replacement therapies being studied for prophylactic treatment of bleeding disorders.
Concizumab-Mtci is an experimental antibody therapy targeting TFPI to prevent bleeding in hemophilia patients.
Key facts at a glance
- RxNorm
- 2708340
- Generic
- Concizumab-Mtci
- Class
- pin-variant
- Brands
- Alhemo
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Under investigation for routine prophylaxis to prevent or reduce bleeding episodes in individuals with hemophilia A or B, with or without inhibitors. May offer an alternative for patients who have developed inhibitors to standard factor replacement therapy.
Functions as a monoclonal antibody that binds to and inhibits tissue factor pathway inhibitor (TFPI), a natural anticoagulant protein. By blocking TFPI, the medication promotes the generation of thrombin, thereby enhancing clot formation and reducing bleeding risk.
This is an investigational agent not yet approved by regulatory authorities. Administered via subcutaneous injection. Clinical trials are ongoing to evaluate safety and efficacy. Patients should only use this medication under supervision in clinical study settings until regulatory approval is obtained.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy