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Copper Sulfate

Published: July 26, 2026Updated: August 27, 2026

Copper sulfate is a copper salt compound primarily used as an agricultural fungicide and algaecide, as well as in water treatment and industrial applications. In veterinary medicine, it may be used to address copper deficiencies in livestock. It is classified under ATC group V03 (all other therapeutic products) rather than as a conventional medication.

Quick summary

Copper sulfate is primarily an agricultural and industrial compound used as a fungicide and algaecide, with limited veterinary applications for copper deficiency.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ATC
V03AB20
RxNorm
2670
Generic
Copper Sulfate
Class
atc-v03
Brands
Hemocyte Plus, Hemax, Macuvite with Lutein, Lactocal, Concept OB, Tandem Plus, Multitrace-4, Multitrace-5, Multrys, Tralement
Availability
otc
Pregnancy
A
Lactation
safe
Half-life (h)
0
Onset (min)
0
Duration (h)
0
Routes
oral, intravenous
Forms
tablet, capsule, injectable solution, powder
Regions
United States, Canada, European Union, United Kingdom, Australia
Monitoring
serum copper, ceruloplasmin, liver function tests, complete blood count

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
2mg elemental copper daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
1mg elemental copper daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
2mg elemental copper daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Single dose of approximately 10 grams may cause serious toxicity and potentially fatal outcomes
Chronic overdose: Prolonged exposure to copper leading to accumulation and hepatic toxicity
Immediate actions
Gastric lavage within 1-2 hours of ingestion, activated charcoal administration, supportive care, hemodynamic monitoring
Antidote
Penicillamine or EDTA (ethylenediaminetetraacetic acid)(Chelation therapy is effective when initiated early to bind circulating copper)
Poison Control: 1-800-222-1222

Special Populations

12 groups
⚠

pregnancy

first trimester
caution
FDA Category
C
Dose Adjustment

use only if copper deficiency confirmed

Key Recommendations

copper supplementation during pregnancy should only be considered when deficiency is documented through laboratory testing

Monitor

regular serum copper and ceruloplasmin monitoring

Use with caution and monitor for adverse effects.

⚠

pregnancy

second trimester
caution
FDA Category
C
Dose Adjustment

use only if copper deficiency confirmed

Key Recommendations

continue supplementation only if benefits outweigh risks and deficiency is documented

Monitor

regular serum copper monitoring

Use with caution and monitor for adverse effects.

⚠

pregnancy

third trimester
caution
FDA Category
C
Dose Adjustment

use only if copper deficiency confirmed

Key Recommendations

copper requirements increase in third trimester but supplementation should be medically supervised

Monitor

regular monitoring of copper status

Use with caution and monitor for adverse effects.

⚠

lactation

breastfeeding
caution
FDA Category
C
Dose Adjustment

adjust dose based on maternal copper status

Key Recommendations

copper is secreted in breast milk; supplementation should be based on maternal copper levels

Monitor

monitor maternal and infant copper levels if supplementing

Use with caution and monitor for adverse effects.

⚠

pediatric_age

infants 0 12 months
caution
FDA Category
C
Dose Adjustment

weight-based dosing under medical supervision

Key Recommendations

use only for documented copper deficiency or wilson's disease under pediatric supervision

Monitor

regular serum copper and ceruloplasmin monitoring

Use with caution and monitor for adverse effects.

⚠

pediatric_age

children 1 12 years
caution
FDA Category
C
Dose Adjustment

weight-based dosing typically 50-100 mcg copper daily

Key Recommendations

typically used for wilson's disease or documented deficiency under physician supervision

Monitor

regular monitoring of copper levels and liver function

Use with caution and monitor for adverse effects.

⚠

geriatric

elderly 65 plus
caution
FDA Category
C
Dose Adjustment

start with lower dose and titrate based on response

Key Recommendations

elderly patients may have altered copper metabolism; monitor closely for toxicity

Monitor

regular serum copper monitoring and assessment of liver function

Use with caution and monitor for adverse effects.

⚠

renal_impairment

mild renal impairment
caution
FDA Category
C
Dose Adjustment

no major dose adjustment typically required

Key Recommendations

copper is primarily excreted via biliary route; monitor copper levels

Monitor

monitor serum copper levels periodically

Use with caution and monitor for adverse effects.

⚠

renal_impairment

severe renal impairment
caution
FDA Category
C
Dose Adjustment

reduce dose and extend dosing interval

Key Recommendations

use with caution; copper levels should be monitored closely

Monitor

frequent serum copper and ceruloplasmin monitoring

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

mild hepatic impairment
caution
FDA Category
C
Dose Adjustment

use with caution

Key Recommendations

copper metabolism is hepatic; monitor liver function tests

Monitor

regular liver function tests and serum copper monitoring

Use with caution and monitor for adverse effects.

✗

hepatic_impairment

severe hepatic impairment
unsafe
FDA Category
C
Dose Adjustment

avoid unless benefits outweigh risks

Key Recommendations

avoid copper supplementation in severe hepatic impairment due to impaired copper metabolism and excretion

Monitor

frequent monitoring if use is unavoidable

Use of this medication in this population requires careful consideration of risks and benefits.

⚠

alcohol_users

chronic alcohol consumption
caution
FDA Category
C
Dose Adjustment

use with caution and monitor closely

Key Recommendations

alcohol affects copper metabolism and may increase copper levels; avoid excessive supplementation

Monitor

regular serum copper and liver function monitoring

Use with caution and monitor for adverse effects.

Statistics and clinical data

prescribingEPA
2023

Commonly used since

Value:Early 1900s

General usage information for agricultural and industrial applications

drug_classFDA
2023

Drug class

Value:Trace element supplement / Agricultural fungicide

Classification as dietary supplement and pesticide active ingredient

usageEPA
2023

Common uses

Value:Agricultural fungicide, Pond treatment, Dietary copper supplement

Primary therapeutic and agricultural applications

safetyEPA
2023

Toxicity class

Value:Moderately toxic (EPA Category II)

Toxicity classification for human exposure

This compound is primarily used for agricultural purposes to control fungal diseases in crops and as an algaecide for water treatment. In veterinary medicine, it may be used for copper deficiency in animals. It is not typically used as a conventional medication in human healthcare.

Copper sulfate works by releasing copper ions that are toxic to fungi, algae, and certain microorganisms. The exact mechanism varies by application—agricultural uses target plant pathogens while water treatment applications control unwanted biological growth.

Copper sulfate is toxic if ingested and must be handled with appropriate protective equipment. Agricultural use is regulated to prevent environmental contamination. Medical use is extremely limited, and it should not be used as a substitute for prescribed medications without professional guidance.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy