Corticorelin Ovine
Corticorelin Ovine is a synthetic form of corticotropin-releasing hormone (CRH) derived from sheep. It is primarily used as a diagnostic agent to evaluate the function of the hypothalamic-pituitary-adrenal (HPA) axis. This medication helps healthcare providers assess pituitary gland function and diagnose certain endocrine disorders.
Corticorelin Ovine is a diagnostic medication used to test pituitary gland function by stimulating ACTH release.
Key facts at a glance
- RxNorm
- 74671
- Generic
- Corticorelin Ovine
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to diagnose and evaluate Cushing's syndrome, distinguish between pituitary and ectopic sources of ACTH production, assess pituitary gland function, and evaluate the integrity of the hypothalamic-pituitary-adrenal axis.
As a synthetic CRH analog, it binds to CRH receptors in the anterior pituitary gland, stimulating the release of adrenocorticotropic hormone (ACTH) from corticotroph cells. This cascade leads to cortisol production from the adrenal glands, allowing clinicians to assess the responsiveness of the HPA axis.
Should only be administered by healthcare professionals experienced in endocrine testing. May cause transient flushing, warmth, or mild hypotension. Use with caution in patients with asthma or allergies. Results should be interpreted in conjunction with clinical findings and other laboratory tests.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy