Corticorelin Ovine Triflutate
Corticorelin Ovine Triflutate is a synthetic form of corticotropin-releasing hormone (CRH) derived from sheep. It is primarily used as a diagnostic agent to evaluate pituitary and adrenal gland function by stimulating ACTH release. This medication helps clinicians differentiate between pituitary and adrenal causes of cortisol-related disorders.
A diagnostic agent used to assess pituitary and adrenal gland function by stimulating ACTH release.
Key facts at a glance
- RxNorm
- 74670
- Generic
- Corticorelin Ovine Triflutate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used for differential diagnosis of Cushing's syndrome to distinguish between pituitary-dependent and adrenal-dependent disease. Also used to evaluate ACTH deficiency and assess pituitary function in various endocrine disorders.
As a synthetic CRH analog, it binds to CRH receptors on corticotroph cells in the anterior pituitary gland, triggering the release of adrenocorticotropic hormone (ACTH). The subsequent rise in cortisol levels from the adrenal glands is measured to assess the integrity of the hypothalamic-pituitary-adrenal axis.
Administered via intravenous injection typically in specialized endocrine testing facilities. May cause transient flushing, warmth, or mild hypotension. Contraindicated in patients with known hypersensitivity to ovine peptides. Results interpretation requires expertise in endocrinology and should be correlated with clinical presentation and other diagnostic findings.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy