Neomycin, Hydrocortisone, and Polymyxin B
Cortisporin is a brand-name ophthalmic medication combining two antibiotics (neomycin and polymyxin B) with hydrocortisone, a corticosteroid. It is used to treat eye infections and inflammation while preventing bacterial growth. This combination product targets both the infectious and inflammatory components of certain eye conditions.
Cortisporin is an antibiotic-corticosteroid combination eye medication used to treat bacterial eye infections with associated inflammation.
Key facts at a glance
- RxNorm
- 21659
- Generic
- Cortisporin
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of superficial ocular infections caused by susceptible bacteria, including conjunctivitis, keratitis, and other inflammatory conditions of the eye where bacterial infection is present or suspected.
Neomycin and polymyxin B provide broad-spectrum antibacterial coverage by disrupting bacterial cell membranes and protein synthesis. Hydrocortisone reduces inflammation, swelling, and itching by suppressing the local immune response.
For ophthalmic use only. Should not be used for fungal or viral infections. Prolonged use may result in ocular complications including cataracts or glaucoma. Patients with known sensitivity to aminoglycosides (like neomycin) should avoid this medication. A prescription is required.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy