Progesterone
Crinone is a brand-name progesterone gel used primarily to support pregnancy in women undergoing assisted reproductive technology (ART) procedures such as in vitro fertilization (IVF). It is also used for the treatment of secondary amenorrhea (absence of menstrual periods). The medication is administered vaginally and provides localized progesterone supplementation.
Crinone is a vaginal progesterone gel used to support early pregnancy in fertility treatments and to treat menstrual absence.
Key facts at a glance
- RxNorm
- 153581
- Generic
- Crinone
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Crinone is primarily used for progesterone supplementation in women undergoing assisted reproductive technology (ART) procedures, particularly during IVF cycles. It is also prescribed for the treatment of secondary amenorrhea to help induce menstrual bleeding.
Crinone contains natural progesterone in a gel formulation for vaginal administration. The exact mechanism of action is not specified by the manufacturer, but it provides localized progesterone delivery to support the endometrium (uterine lining) and maintain early pregnancy in fertility treatment protocols.
Crinone is available by prescription only and should be used under the guidance of a healthcare provider specializing in fertility treatments. It is contraindicated in patients with known hypersensitivity to progesterone or any components of the gel, undiagnosed vaginal bleeding, or certain medical conditions. Patients should follow their prescribed dosing schedule exactly as directed and report any unusual symptoms to their healthcare provider.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy