Crisaborole
Crisaborole is a topical phosphodiesterase 4 (PDE-4) inhibitor used to treat mild to moderate atopic dermatitis (eczema) in adults and children as young as 3 months old. By inhibiting PDE-4, it increases intracellular cAMP levels, which helps reduce the inflammation and itching associated with eczema.
A topical PDE-4 inhibitor ointment that relieves inflammation and itching from mild to moderate eczema.
Key facts at a glance
- ATC
- D11AH06
- RxNorm
- 1865953
- Generic
- Crisaborole
- Class
- atc-d11
- Brands
- Eucrisa
- Availability
- rx
- Lactation
- unknown
- Routes
- topical
- Forms
- ointment
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Topical treatment of mild to moderate atopic dermatitis (eczema) in adults and pediatric patients 3 months of age and older
Inhibits phosphodiesterase 4 (PDE-4) enzyme, leading to increased intracellular cyclic adenosine monophosphate (cAMP) levels and reduced inflammatory responses that cause eczema symptoms
For topical use only; avoid contact with eyes, mouth, and mucous membranes. Common side effects may include application site burning or stinging. Should not be used on patients with known hypersensitivity to crisaborole. Consult healthcare provider if symptoms do not improve within a reasonable timeframe.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy