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Croscarmellose Sodium

Published: July 26, 2026Updated: August 27, 2026

Croscarmellose Sodium is a pharmaceutical excipient classified as a superdisintegrant. It is not an active medication but is added to tablet and capsule formulations during manufacturing to facilitate the breakdown of solid dosage forms in the gastrointestinal tract, ensuring proper drug dissolution and absorption.

Quick summary

Croscarmellose Sodium is an inactive pharmaceutical ingredient used as a tablet-disintegrating agent rather than a medication for treating any medical condition.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
1310573
Generic
Croscarmellose Sodium
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Croscarmellose Sodium is not prescribed to treat any medical condition. It is used by pharmaceutical manufacturers as an excipient in oral solid dosage forms (tablets and capsules) to ensure proper disintegration and drug release.

As a superdisintegrant, it works primarily through rapid swelling when in contact with water. This swelling creates hydraulic pressure within the tablet matrix, causing it to break apart into smaller particles and allowing the active drug to dissolve and become available for absorption.

As an inactive ingredient (excipient), it is generally recognized as safe by regulatory agencies. However, patients with known sensitivities to croscarmellose or cellulose derivatives should consult their pharmacist. It is always listed on the medication's package insert as an ingredient.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy