Cyclizine
Cyclizine is an antihistamine medication primarily used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness and vestibular disorders. It works by blocking histamine H1 receptors in the brain, reducing signals that trigger the vomiting reflex. This medication is commonly prescribed for patients experiencing travel-related nausea or those with inner ear conditions causing vertigo.
Cyclizine is an antihistamine used to prevent motion sickness and treat nausea and vertigo.
Key facts at a glance
- ATC
- R06AE03
- RxNorm
- 2977
- Generic
- Cyclizine
- Class
- atc-r06
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet, solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Cyclizine is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness, vestibular disorders, and vertigo. It may also be used for nausea following surgery or chemotherapy.
Cyclizine is an H1 antihistamine that works by blocking histamine receptors in the vomiting center of the brain. It also has anticholinergic properties that help reduce nausea and vomiting signals from the inner ear.
May cause drowsiness; avoid alcohol and operating machinery. Use with caution in patients with glaucoma, urinary retention, or benign prostatic hyperplasia. Not recommended during early pregnancy unless clearly necessary. Available in tablet and injection forms.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy