Cyclizine Hydrochloride
Cyclizine Hydrochloride is a first-generation antihistamine with antiemetic properties used primarily to prevent and treat nausea, vomiting, and dizziness. It is commonly prescribed for motion sickness and vestibular disorders such as vertigo and Ménière's disease.
Cyclizine Hydrochloride is an antihistamine used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness and vestibular disorders.
Key facts at a glance
- RxNorm
- 155017
- Generic
- Cyclizine Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention and treatment of nausea and vomiting, particularly motion sickness, as well as vertigo and dizziness associated with vestibular disorders like Ménière's disease.
Works as an H1 antihistamine by blocking histamine receptors in the vomiting center of the brain and has anticholinergic properties that help reduce nausea and vomiting signals.
May cause drowsiness; avoid alcohol and driving until aware of effects. Should be used with caution in patients with glaucoma, urinary retention, or severe heart disease. Not recommended during pregnancy unless clearly needed.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy