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Cyclizine Lactate

Published: July 26, 2026Updated: August 27, 2026

Cyclizine Lactate is a first-generation antihistamine with anticholinergic properties, primarily used to prevent and treat nausea, vomiting, and vertigo. It is commonly administered intravenously in acute clinical settings and may also be used for motion sickness prevention.

Quick summary

Cyclizine Lactate is an antihistamine antiemetic used to treat nausea, vomiting, and vertigo.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
91071
Generic
Cyclizine Lactate
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Prevention and treatment of nausea and vomiting associated with motion sickness, vertigo (including Meniere's disease), postoperative settings, and chemotherapy-induced nausea where appropriate.

Acts as an H1 antihistamine receptor antagonist with anticholinergic properties, blocking signals in the vomiting center of the brain and reducing vestibular system stimulation that triggers nausea and vomiting.

May cause drowsiness and should be used with caution when operating machinery. Should be avoided in patients with angle-closure glaucoma, urinary retention, or severe liver impairment. May interact with other CNS depressants. The intravenous lactate formulation provides rapid onset when oral administration is not feasible.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy