Cyclopentamine Hydrochloride
Cyclopentamine Hydrochloride is a sympathomimetic amine decongestant used primarily to relieve nasal congestion. It works by constricting blood vessels in the nasal passages, reducing swelling and allowing for easier breathing. This medication has largely been replaced by other decongestants in modern clinical practice.
A sympathomimetic nasal decongestant that constricts blood vessels to relieve nasal congestion.
Key facts at a glance
- RxNorm
- 1300303
- Generic
- Cyclopentamine Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of nasal congestion associated with the common cold, sinusitis, or allergic rhinitis. Historically used as a topical nasal decongestant.
Acts as a sympathomimetic amine that stimulates alpha-adrenergic receptors, causing vasoconstriction of the nasal mucosa, which reduces swelling and congestion.
Should be avoided in patients with cardiovascular disease, hypertension, hyperthyroidism, or glaucoma. Prolonged use may lead to rebound congestion. Use with caution in diabetics and those taking MAO inhibitors. Discontinued in many countries due to availability of safer alternatives.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy