Cyclophosphamide Anhydrous
Cyclophosphamide Anhydrous is a chemotherapy medication and immunosuppressant that belongs to the alkylating agent drug class. It works by interfering with DNA synthesis in cells, preventing their replication and growth. This medication is used to treat various cancers including leukemias, lymphomas, and solid tumors, as well as certain autoimmune conditions such as lupus and vasculitis when other treatments have not been effective.
Cyclophosphamide is a powerful alkylating agent used to treat cancers and autoimmune disorders by disrupting DNA replication in rapidly dividing cells.
Key facts at a glance
- RxNorm
- 1545988
- Generic
- Cyclophosphamide Anhydrous
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Cyclophosphamide is used to treat various malignancies including acute and chronic leukemias, Hodgkin's and non-Hodgkin lymphomas, multiple myeloma, neuroblastoma, retinoblastoma, and solid tumors such as breast and ovarian cancer. It is also used for severe autoimmune conditions including systemic lupus erythematosus, vasculitis, multiple sclerosis, and to prevent organ rejection in bone marrow transplants.
As an alkylating agent, cyclophosphamide is metabolized in the liver to active compounds that cross-link DNA strands, preventing DNA replication and cell division. This affects all rapidly dividing cells, including cancer cells and immune cells, leading to cell death.
Cyclophosphamide carries significant risks including bone marrow suppression, hemorrhagic cystitis (requiring adequate hydration), increased infection risk, infertility, and potential long-term toxicity. Treatment requires close medical supervision with regular monitoring of blood counts and organ function. It may interact with other immunosuppressants, anticoagulants, and myelosuppressive drugs. Effective contraception is recommended during and after treatment due to teratogenic effects.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy