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Cyclosporine Microemulsion

Published: July 26, 2026Updated: August 25, 2026

Cyclosporine Microemulsion is an ophthalmic immunomodulatory medication used to treat chronic dry eye disease by increasing natural tear production. It works by reducing ocular surface inflammation, allowing the lacrimal glands to resume normal function and improve eye lubrication.

Quick summary

An eye drop medication that treats chronic dry eye by reducing inflammation and increasing tear production.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
484788
Generic
Cyclosporine Microemulsion
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Cyclosporine Microemulsion is indicated for the treatment of keratoconjunctivitis sicca (dry eye syndrome), particularly in cases where inflammation contributes to reduced tear production. It is used to increase tear production in patients with chronic dry eye disease.

As a calcineurin inhibitor, cyclosporine suppresses T-lymphocyte activation and reduces inflammatory cytokine production on the ocular surface. The microemulsion formulation enhances drug penetration, allowing the medication to reduce inflammation and restore normal lacrimal gland function, thereby increasing natural tear secretion.

May cause temporary eye burning, stinging, or blurred vision upon application. Patients should avoid touching the tip of the container to prevent contamination. Contact lenses should be removed before instillation and may be reinserted after 15 minutes. Treatment effects may take several weeks to become apparent. Use with caution in patients with active ocular infections.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy