Cyproheptadine
Cyproheptadine is a first-generation antihistamine with additional serotonin-blocking properties, making it useful for treating allergic conditions such as hay fever, allergic rhinitis, and urticaria. Due to its appetite-stimulating effects, it is also prescribed for weight gain in patients with appetite loss.
Cyproheptadine is an antihistamine used for allergies and appetite stimulation.
Key facts at a glance
- ATC
- R06AX02
- RxNorm
- 3013
- Generic
- Cyproheptadine
- Class
- atc-r06
- Brands
- —
- Availability
- rx
- Pregnancy
- B
- Lactation
- safe
- Routes
- oral
- Forms
- solution, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of seasonal and perennial allergic rhinitis, allergic conjunctivitis, urticaria (hives), and other allergic skin reactions. Also prescribed off-label for appetite stimulation and migraine prevention.
Blocks H1 histamine receptors and serotonin receptors, preventing allergic symptoms caused by histamine release and reducing migraine frequency through serotonin antagonism.
May cause drowsiness and should be used with caution in elderly patients. Avoid in patients with glaucoma, urinary retention, or those taking MAO inhibitors. Alcohol may enhance sedative effects.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy