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Cyproheptadine Hydrochloride

Published: July 26, 2026Updated: August 25, 2026

Cyproheptadine Hydrochloride is an antihistamine medication that blocks histamine and serotonin receptors in the body. It is primarily used to treat allergic reactions, allergic rhinitis, and skin conditions like urticaria, and may also be prescribed to stimulate appetite. This medication is available by prescription and should be taken as directed by a healthcare provider.

Quick summary

Cyproheptadine is an antihistamine used for allergies, itching, and appetite stimulation that works by blocking histamine and serotonin.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
104592
Generic
Cyproheptadine Hydrochloride
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of allergic conditions including seasonal allergies, allergic rhinitis, skin allergies, and cold-induced urticaria; may also be used as an appetite stimulant and for migraine prevention in some cases.

Functions as a first-generation antihistamine by blocking H1 receptors, and also acts as a serotonin antagonist, which contributes to its anti-allergic and appetite-stimulating effects.

May cause drowsiness; avoid alcohol and operating machinery until you know how it affects you. Inform your doctor of any existing conditions, especially glaucoma, asthma, or urinary problems. Not recommended during pregnancy without medical consultation.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy