Cytomegalovirus immune globulin
Cytogam is a brand-name cytomegalovirus immune globulin (CMV-IGIV) product that provides passive immunization against cytomegalovirus infection. It is primarily used in immunocompromised patients, particularly those who have undergone organ or bone marrow transplants, to help prevent CMV disease. This medication is administered intravenously and works by supplying ready-made antibodies to help the recipient's immune system fight CMV infection.
Cytogam is a CMV-specific immune globulin used to prevent cytomegalovirus disease in transplant recipients and other immunocompromised patients.
Key facts at a glance
- RxNorm
- 216315
- Generic
- Cytogam
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Cytogam is indicated for the prophylaxis of cytomegalovirus (CMV) disease in recipients of bone marrow transplants and kidney transplants. It is specifically used in seronegative transplant recipients who receive organs from CMV-seropositive donors, as well as in some cases for the treatment of established CMV infection in immunocompromised patients.
Cytogam contains pooled immune globulin G (IgG) antibodies specifically targeted against cytomegalovirus. It provides passive immunity by delivering high-titer CMV-neutralizing antibodies directly into the bloodstream, which help prevent or attenuate CMV infection and disease until the patient's own immune system can mount an effective response.
Cytogam is administered intravenously under medical supervision. Common side effects may include headache, nausea, and mild fever. It is contraindicated in patients with known hypersensitivity to immune globulin products or selective IgA deficiency. This medication may interfere with live virus vaccines, and patients should be monitored for signs of infusion-related reactions.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy