Dabrafenib Mesylate
Dabrafenib Mesylate is a targeted cancer medication called a BRAF kinase inhibitor used to treat certain melanomas and other cancers with specific BRAF gene mutations. It works by blocking abnormal signals that drive cancer cell growth and is typically given to patients whose tumors have tested positive for BRAF V600E or V600K mutations.
A targeted therapy for BRAF mutation-positive cancers that blocks cancer cell growth signals.
Key facts at a glance
- RxNorm
- 1425222
- Generic
- Dabrafenib Mesylate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats melanoma and certain other cancers with BRAF V600 mutations, including Erdheim-Chester disease and Langerhans cell histiocytosis. Requires confirmed BRAF mutation testing before use.
Inhibits mutated BRAF serine-threonine kinase, blocking abnormal signaling pathways that fuel uncontrolled cancer cell proliferation and survival.
May be used alone or with trametinib (MEK inhibitor) to reduce resistance. Can cause new skin lesions, fever, and requires regular skin monitoring. Not effective in BRAF wild-type cancers.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy