Skip to content

Daclatasvir

Published: July 26, 2026Updated: August 25, 2026

Daclatasvir is a direct-acting antiviral agent used to treat chronic hepatitis C virus (HCV) infection. It works by inhibiting the NS5A protein, which is essential for viral RNA replication, and is typically used in combination with other antiviral medications such as sofosbuvir.

Quick summary

Daclatasvir is an antiviral medication used to treat chronic hepatitis C infection, typically as part of combination therapy.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ATC
J05AP07
RxNorm
1606218
Generic
Daclatasvir
Class
atc-j05
Brands
—
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of chronic hepatitis C virus (HCV) infection in adults, including patients with or without cirrhosis. It is indicated for use in combination with other antiviral agents and is effective against multiple HCV genotypes.

Daclatasvir is a potent inhibitor of the HCV non-structural protein 5A (NS5A), which plays a critical role in viral RNA replication and virion assembly. By blocking this protein, it prevents the virus from multiplying and spreading.

Daclatasvir should not be used as monotherapy and must be combined with other antiviral medications. It requires a prescription and medical supervision. Patients should be monitored for potential drug interactions and should have liver function assessed during treatment. Effectiveness varies depending on HCV genotype and prior treatment history.

Official drug label

WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy