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Danofloxacin Mesylate

Published: July 26, 2026Updated: August 25, 2026

Danofloxacin Mesylate is a fluoroquinolone antibiotic developed for veterinary use in food-producing animals. It is used to treat bacterial respiratory infections, particularly those caused by Pasteurella and Mannheimia species in cattle and sheep. The medication works by inhibiting bacterial DNA replication enzymes, effectively stopping the growth and spread of susceptible bacteria.

Quick summary

Danofloxacin Mesylate is a veterinary fluoroquinolone antibiotic used to treat respiratory bacterial infections in livestock.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
1358487
Generic
Danofloxacin Mesylate
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treats bacterial respiratory tract infections in cattle and sheep, including those caused by Pasteurella multocida, Mannheimia haemolytica, and other susceptible organisms. May also be used for enteric and systemic bacterial infections in various animal species.

As a fluoroquinolone, danofloxacin inhibits bacterial DNA gyrase and topoisomerase IV enzymes, which are essential for bacterial DNA replication, transcription, and repair. This bactericidal action prevents bacterial cell division and leads to bacterial death.

For veterinary use only. Fluoroquinolones should be used with caution due to potential for tendon damage and cartilage abnormalities. Withdrawal times must be observed in food-producing animals. Resistance to fluoroquinolones is a growing concern, so appropriate diagnostic testing and antimicrobial stewardship are recommended.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy