Dantrolene
Dantrium (dantrolene) is a muscle relaxant medication that works directly on skeletal muscle to reduce spasticity. It is primarily used to manage spasticity caused by conditions such as spinal cord injury, stroke, cerebral palsy, and multiple sclerosis, as well as to prevent and treat malignant hyperthermia during surgical procedures.
Dantrium is a muscle relaxant used to treat spasticity from neurological conditions and prevent malignant hyperthermia during surgery.
Key facts at a glance
- RxNorm
- 3104
- Generic
- Dantrium
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of spasticity associated with spinal cord injury, stroke, cerebral palsy, multiple sclerosis, and other neurological conditions; prevention and treatment of malignant hyperthermia crisis.
Dantrolene acts directly on skeletal muscle by inhibiting calcium release from the sarcoplasmic reticulum, thereby reducing muscle contraction and spasticity.
May cause drowsiness, dizziness, and weakness. Can rarely cause severe liver toxicity requiring monitoring. Avoid alcohol and other CNS depressants. Must be used cautiously in patients with cardiac or pulmonary impairment. Not for use in patients with active liver disease.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy