Diphtheria, tetanus, pertussis vaccine
Daptacel is a brand-name combination vaccine that protects children against three serious bacterial diseases: diphtheria, tetanus, and pertussis (whooping cough). It is part of the DTaP vaccine series typically administered to infants and young children starting at 2 months of age. The vaccine works by stimulating the immune system to produce protective antibodies against these pathogens without causing the diseases themselves.
Daptacel is a pediatric DTaP vaccine that protects against diphtheria, tetanus, and pertussis in young children.
Key facts at a glance
- RxNorm
- 352572
- Generic
- Daptacel
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of diphtheria, tetanus (lockjaw), and pertussis (whooping cough) in infants and children from 6 weeks through 6 years of age. It is part of the routine childhood immunization schedule.
Daptacel contains diphtheria toxoid, tetanus toxoid, and acellular pertussis antigens that stimulate the immune system to produce protective antibodies against these bacteria and their toxins. Unlike whole-cell pertussis vaccines, the acellular formulation typically causes fewer side effects.
This vaccine is contraindicated in children with a history of severe allergic reaction to any component or who developed encephalopathy within 7 days of a previous pertussis vaccine dose. Common side effects may include fever, redness at the injection site, and fussiness. Vaccination should be postponed during moderate or severe illness. Healthcare providers should have epinephrine available in case of rare anaphylactic reactions.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy