Daratumumab-Fihj
Daratumumab-Fihj is a biosimilar monoclonal antibody targeting CD38, a protein found on the surface of plasma cells. It is primarily used in the treatment of multiple myeloma and other plasma cell malignancies, working by binding to CD38 and triggering immune-mediated destruction of cancer cells.
A CD38-targeting monoclonal antibody biosimilar used to treat multiple myeloma and related plasma cell disorders.
Key facts at a glance
- RxNorm
- 2375130
- Generic
- Daratumumab-Fihj
- Class
- pin-variant
- Brands
- Darzalex Faspro
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of multiple myeloma (as monotherapy or in combination with other agents), often in patients who have received prior therapies. May also be used in amyloidosis and other CD38-positive hematologic malignancies.
Binds to the CD38 antigen on the surface of malignant plasma cells, leading to cell death through multiple mechanisms including complement-dependent cytotoxicity (CDC), antibody-dependent cellular cytotoxicity (ADCC), and induction of apoptosis.
Administered via intravenous infusion. Common side effects include infusion reactions, fatigue, nausea, and cytopenias. Requires pre-medication with corticosteroids, antihistamines, and antipyretics. May interfere with blood type testing and requires monitoring for infections and immune suppression.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy