Darunavir Ethanolate
Darunavir ethanolate is an HIV protease inhibitor used in the treatment of HIV-1 infection. It works by blocking the protease enzyme that the virus needs to replicate, and is always used in combination with other antiretroviral medications, typically with a pharmacokinetic booster like ritonavir or cobicistat to enhance its effectiveness.
Darunavir ethanolate is an HIV protease inhibitor used with other antiretrovirals to treat HIV-1 infection.
Key facts at a glance
- RxNorm
- 644682
- Generic
- Darunavir Ethanolate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of HIV-1 infection in adults and children, particularly useful in treatment-experienced patients who have developed resistance to other protease inhibitors. Used as part of combination antiretroviral therapy.
As a protease inhibitor, darunavir binds to the active site of the HIV-1 protease enzyme, preventing it from cleaving viral polyprotein precursors into functional proteins needed for viral replication.
Must be taken with food and always used in combination with other antiretrovirals. Requires dose adjustment in patients with hepatic impairment. Monitor liver function and for drug interactions, as it interacts with many medications metabolized by CYP3A4.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy