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Darunavir Propylene Glycolate

Published: July 26, 2026Updated: August 25, 2026

Darunavir Propylene Glycolate is an antiretroviral medication classified as a protease inhibitor variant used in the treatment of HIV-1 infection. It is typically prescribed as part of combination antiretroviral therapy for treatment-experienced patients, including those with resistance to other protease inhibitors.

Quick summary

Darunavir Propylene Glycolate is an HIV protease inhibitor used in combination therapy for patients with HIV-1 infection.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
2670599
Generic
Darunavir Propylene Glycolate
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of HIV-1 infection in combination with other antiretroviral agents. Commonly used in treatment-experienced patients who have developed resistance to other antiretroviral medications.

As a protease inhibitor, it targets the HIV-1 protease enzyme, which is essential for the viral replication cycle. By inhibiting this enzyme, the medication prevents the cleavage of viral polyproteins, resulting in the production of immature, non-infectious viral particles.

Should be used with a booster (ritonavir or cobicistat) to enhance pharmacokinetics. Important to ensure patient adherence to reduce risk of resistance development. May interact with multiple medications; review concurrent drug use. Common side effects include rash, nausea, and elevated liver enzymes.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy