Daratumumab
Darzalex Faspro is a combination medication containing the monoclonal antibody daratumumab and hyaluronidase, designed to treat multiple myeloma and AL amyloidosis. It is administered as a subcutaneous injection and works by targeting CD38 proteins found on cancer cells to help destroy them.
A targeted cancer therapy injection for multiple myeloma and AL amyloidosis that works by attacking CD38-positive cells.
Key facts at a glance
- RxNorm
- 2375137
- Generic
- Darzalex Faspro
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of adult patients with multiple myeloma (in combination with other medications or as monotherapy) including newly diagnosed, relapsed, and refractory cases. Also approved for AL amyloidosis.
Contains daratumumab, a monoclonal antibody that binds to the CD38 protein on the surface of cancer cells, triggering multiple immune responses including antibody-dependent cellular cytotoxicity, complement activation, and direct apoptosis to destroy malignant plasma cells.
Administered as a subcutaneous injection, typically over 3-5 minutes. Requires monitoring for infusion-related reactions. May affect blood type testing and cross-matching. Common side effects include fatigue, nausea, upper respiratory infections, and decreased blood counts. Should not be used during pregnancy. Vaccination live vaccines should be avoided during treatment.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy