Daunorubicin Citrate Liposome
Daunorubicin Citrate Liposome is a liposomal formulation of the anthracycline chemotherapy agent daunorubicin. It is primarily used to treat advanced HIV-associated Kaposi's sarcoma in patients who have failed or are intolerant to other treatments. The liposomal delivery system allows for targeted drug delivery to tumor sites while potentially reducing toxicity to healthy tissues.
A liposomal anthracycline chemotherapy used for advanced HIV-associated Kaposi's sarcoma.
Key facts at a glance
- RxNorm
- 221087
- Generic
- Daunorubicin Citrate Liposome
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
FDA-approved for the treatment of advanced HIV-associated Kaposi's sarcoma in patients who have progressed on prior systemic therapy or are intolerant to it. May also be used off-label in other malignancies as determined by oncology specialists.
Daunorubicin intercalates into DNA and inhibits topoisomerase II, causing DNA strand breaks that prevent cancer cell replication. The liposomal encapsulation helps concentrate the drug in tumor tissue through enhanced permeability of tumor vasculature, potentially improving efficacy while reducing exposure to normal tissues.
Administered intravenously by healthcare professionals experienced in chemotherapy. Requires regular monitoring of cardiac function (ECHO/MUGA scans) and complete blood counts. Common adverse effects include bone marrow suppression, infusion reactions, nausea, and fatigue. Cardiotoxicity and hepatotoxicity are potential serious concerns. Contraindicated in pregnancy.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy