Daybue
Daybue is a prescription medication approved by the FDA for the treatment of Rett syndrome in adults and pediatric patients 2 years of age and older. It is the first and only FDA-approved drug specifically indicated for Rett syndrome, addressing a significant unmet medical need for patients with this rare genetic neurological disorder.
Daybue is an FDA-approved prescription medication for treating Rett syndrome in adults and children 2 years and older.
Key facts at a glance
- RxNorm
- 2632858
- Generic
- Daybue
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Daybue is indicated for the treatment of Rett syndrome in adults and pediatric patients 2 years of age and older. Rett syndrome is a rare genetic neurological disorder that primarily affects females and is characterized by problems with brain development, leading to severe motor and cognitive impairments.
The exact mechanism of action of Daybue is not fully established. Daybue contains the active ingredient trofinetide, which is a synthetic analogue of a naturally occurring neuropeptide.
Daybue is taken orally twice daily. Common side effects may include diarrhea and vomiting. Patients should be monitored for weight loss and suicidal thoughts or behaviors. The medication should be stored properly and must be prescribed by a healthcare provider familiar with the condition.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy