Desmopressin
DDAVP (desmopressin) is a synthetic hormone that mimics the action of vasopressin (ADH), primarily used to reduce excessive urination and manage certain bleeding disorders. It works by helping the kidneys conserve water and is commonly prescribed for central diabetes insipidus, nocturnal enuresis, and hemophilia A.
DDAVP is a hormone replacement therapy that reduces urine output and is also used for certain bleeding disorders.
Key facts at a glance
- RxNorm
- 203658
- Generic
- Ddavp
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats central diabetes insipidus (excessive thirst and urination), nocturnal enuresis (bedwetting), and hemophilia A or von Willebrand disease (to promote clotting factor release).
Mimics natural antidiuretic hormone (vasopressin) by binding to V2 receptors in the kidneys, allowing water reabsorption and concentrating urine. May also stimulate release of Factor VIII and von Willebrand factor to support clotting.
Available as nasal spray, oral tablets, and injection forms. Use with caution in patients with heart conditions, hypertension, or hyponatremia. Avoid excessive fluid intake during treatment to prevent water intoxication. Monitor sodium levels regularly.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy