Delafloxacin Meglumine
Delafloxacin Meglumine is a fluoroquinolone antibiotic used primarily to treat acute bacterial skin and skin structure infections (ABSSSI), including those caused by resistant organisms like MRSA. It works by inhibiting bacterial DNA gyrase and topoisomerase IV enzymes, disrupting bacterial DNA replication. This medication is typically reserved for cases where other antibiotics may not be appropriate due to its potent broad-spectrum activity against both gram-positive and gram-negative bacteria.
Delafloxacin Meglumine is a fluoroquinolone antibiotic for treating serious skin infections caused by resistant bacteria including MRSA.
Key facts at a glance
- RxNorm
- 1927662
- Generic
- Delafloxacin Meglumine
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats acute bacterial skin and skin structure infections (ABSSSI) including cellulitis, wound infections, and abscesses caused by susceptible gram-positive and gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA).
Belongs to the fluoroquinolone class of antibiotics; works by inhibiting two essential bacterial enzymes—DNA gyrase and topoisomerase IV—required for bacterial DNA replication, transcription, and repair, leading to bacterial cell death.
Carries FDA black box warnings for tendinitis, tendon rupture (particularly in patients over 60), peripheral neuropathy, and central nervous system effects. May prolong QT interval and should be avoided in patients with known seizure disorders. Reserved for situations when other antibiotics are not suitable to help preserve fluoroquinolone effectiveness. Administered via intravenous infusion.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy