Delavirdine Mesylate
Delavirdine Mesylate is an antiretroviral medication classified as a non-nucleoside reverse transcriptase inhibitor (NNRTI). It is used in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults. The medication works by inhibiting the reverse transcriptase enzyme, which is essential for viral replication.
Delavirdine Mesylate is an HIV medication that inhibits viral replication by blocking the reverse transcriptase enzyme and is used as part of combination therapy.
Key facts at a glance
- RxNorm
- 142152
- Generic
- Delavirdine Mesylate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Delavirdine Mesylate is indicated for the treatment of HIV-1 infection in combination with other antiretroviral medications. It is typically used in patients who have not responded to other treatment regimens. The medication is always used as part of a combination therapy, never as monotherapy.
Delavirdine Mesylate works as a non-competitive inhibitor of HIV-1 reverse transcriptase. It binds directly to the reverse transcriptase enzyme, blocking its activity and preventing the conversion of viral RNA into DNA. This inhibition disrupts the viral replication cycle and helps reduce viral load.
Delavirdine has been largely replaced by newer NNRTIs with better efficacy and tolerability profiles. It has significant drug interactions with many common medications, including proton pump inhibitors, certain statins, and hormonal contraceptives. Patients should take the medication exactly as prescribed and continue taking it even if they feel well. Treatment regimens should be determined by healthcare providers specializing in HIV care.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy