Metyrosine
Demser (metyrosine) is a brand-name medication used to manage symptoms of pheochromocytoma, a rare tumor of the adrenal gland that causes excessive production of catecholamines like epinephrine and norepinephrine. It is typically prescribed to help control blood pressure and other symptoms before surgical removal of the tumor.
Demser is used to treat pheochromocytoma by reducing catecholamine production to control blood pressure and symptoms.
Key facts at a glance
- RxNorm
- 151594
- Generic
- Demser
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Demser is primarily used to treat pheochromocytoma, a catecholamine-secreting tumor of the adrenal glands. It is often given before surgery to help manage blood pressure and reduce cardiovascular complications during the procedure.
Metyrosine works by inhibiting tyrosine hydroxylase, the enzyme responsible for the rate-limiting step in catecholamine synthesis. By blocking this enzyme, it reduces the production of epinephrine and norepinephrine, thereby lowering blood pressure and reducing associated symptoms.
Patients should maintain adequate fluid intake while taking Demser to reduce the risk of crystalluria. Common side effects include sedation, diarrhea, and extrapyramidal symptoms. Regular monitoring of blood pressure and cardiac function is recommended during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy