Estradiol cypionate
Depo-Estradiol is an injectable estrogen hormone medication used to treat conditions related to estrogen deficiency in women. It contains estradiol cypionate and is commonly prescribed for symptom relief during menopause and for certain hormonal disorders. This medication is administered via intramuscular injection by healthcare professionals.
Depo-Estradiol is an injectable estrogen therapy used to treat menopause symptoms and hormone deficiencies in women.
Key facts at a glance
- RxNorm
- 48876
- Generic
- Depo-Estradiol
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats symptoms of menopause including hot flashes, night sweats, and vaginal dryness; also used for estrogen replacement therapy in women with ovarian failure or hypogonadism, and may be used in certain cancer treatments affecting hormone-responsive tissues.
Provides exogenous estrogen (estradiol cypionate) that mimics the body's natural estrogen, binding to estrogen receptors in various tissues to supplement or replace endogenous hormone production.
Should not be used during pregnancy; may increase risk of blood clots, stroke, or certain cancers with long-term use; requires regular medical monitoring; injectable form administered by healthcare providers; other medications and medical conditions may interact with estrogen therapy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy