Medroxyprogesterone acetate
Depo-Subq Provera is a progestin-only hormonal contraceptive administered as a subcutaneous injection every three months. It contains medroxyprogesterone acetate and works by preventing ovulation and thickening cervical mucus to prevent pregnancy. This brand-name medication is designed for women seeking long-acting reversible contraception.
Depo-Subq Provera is a quarterly injectable progestin-only birth control option that prevents pregnancy by stopping ovulation and altering cervical mucus.
Key facts at a glance
- RxNorm
- 545467
- Generic
- Depo-Subq Provera
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of pregnancy in women of reproductive age who have chosen subcutaneous injection as their method of contraception. It is a long-acting reversible contraceptive suitable for those who prefer an alternative to daily oral contraceptives or intrauterine devices.
As a progestin-only contraceptive, it primarily works by suppressing ovulation, thinning the uterine lining, and thickening cervical mucus to prevent sperm from reaching an egg. The active ingredient medroxyprogesterone acetate is released gradually into the bloodstream following subcutaneous administration.
This is a brand-name medication administered by subcutaneous injection approximately every 12-14 weeks by a healthcare provider. Common side effects may include menstrual changes, weight fluctuations, and mood changes. It does not protect against sexually transmitted infections. Women should discuss their complete medical history with a healthcare provider before starting treatment, particularly regarding history of breast cancer, liver disease, or unexplained vaginal bleeding.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy