Dequalinium
Dequalinium is a topical antiseptic medication belonging to the quaternary ammonium compound family. It is primarily used to treat bacterial and fungal infections of the vaginal area, including bacterial vaginosis and mixed infections, as well as for oral and wound care applications. The medication works by disrupting the cell membranes of microorganisms, effectively killing or inhibiting the growth of bacteria and fungi.
Dequalinium is a topical antiseptic used to treat vaginal, oral, and skin infections by killing bacteria and fungi.
Key facts at a glance
- ATC
- D08AH01
- RxNorm
- 3226
- Generic
- Dequalinium
- Class
- atc-d08
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of bacterial vaginosis, vaginal candidiasis, mixed vaginal infections, mouth infections (such as gingivitis and mouth ulcers), and wound disinfection. Available as vaginal tablets, mouthwash, lozenges, and topical solutions.
As a cationic surfactant and quaternary ammonium compound, dequalinium exerts antimicrobial activity by disrupting the integrity of bacterial and fungal cell membranes, leading to cell death. It is effective against a broad spectrum of gram-positive bacteria, some gram-negative bacteria, and fungi.
For topical and vaginal use only; do not swallow vaginal tablets. May cause local irritation or allergic reactions. Contraindicated in individuals with known hypersensitivity to quaternary ammonium compounds. Avoid contact with eyes. Pregnant or breastfeeding women should consult a healthcare provider before use. Effectiveness may be reduced if used with soaps or anionic surfactants.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy