Desipramine Dibudinate
Desipramine Dibudinate is a tricyclic antidepressant salt form used primarily to treat major depressive disorder. It works by inhibiting the reuptake of norepinephrine and serotonin in the central nervous system. This medication is typically reserved for patients who have not responded to other antidepressant therapies.
Desipramine Dibudinate is a tricyclic antidepressant used for depression when other treatments have failed.
Key facts at a glance
- RxNorm
- 1099738
- Generic
- Desipramine Dibudinate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of major depressive disorder; may be used off-label for neuropathic pain, attention deficit hyperactivity disorder, or smoking cessation in some cases.
Inhibits norepinephrine and serotonin reuptake at presynaptic neurons, increasing available neurotransmitters in the synaptic cleft to improve mood and emotional state.
Requires careful monitoring for suicidal ideation especially in young adults; may cause sedation, dry mouth, constipation, urinary retention, and cardiovascular effects; avoid abrupt discontinuation; contraindicated shortly after MAOI use; full therapeutic effect may take 2-4 weeks.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy